Bayes, prevalence, & PPV

While I was taking a course (online) about Bayesian statistics, one of the intro sections had an example of calculating the positive predictive value of a screening test using Bayes theorem. This reminded me of some really old posts that I came across in college particularly regarding screening tests (e.g. mammography).

I’m a big fan of interactive apps to display principles, so I took a shot at developing my own. This Shiny app shows exactly how sensitive the positive predictive value is to the underlying prevalence. Granted this is something that I knew conceptually, but actually being able to interact with the data really reinforces the degree of skepticism we should have towards positive screening tests in populations with a low prevalence.

Below is an iframe of the app, but I’d recommend visiting the full app if you want to play around with it.

Hunter Ratliff, MD, MPH
Hunter Ratliff, MD, MPH
Infectious Diseases Fellow

My research interests include epidemiology, social determinants of health, and reproducible research.

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